[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"refractory-melasma\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:refractory-melasma":39},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":10,"sex":15,"minAge":16,"maxAge":17,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":4,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":28,"lastUpdatePostDateStruct":29,"startDateStruct":32,"completionDateStruct":34,"leadSponsor":36,"locationsCount":5},"100556275",false,"NCT06522984","Fractional Erbium YAG Laser vs Intradermal and Systemic Tranexamic Acid","Fractional Erbium YAG Laser vs Intradermal and Systemic Tranexamic Acid in Combination With Topical Hydroquinone for Refractory Melasma","Inclusion Criteria:\n\n\\- Patients of both sexes with melasma.\n\nExclusion Criteria:\n\n* Pregnancy\n* Lactation\n* Administration of oral contraceptive pills or any phototoxic drug within 1 month prior to study\n* Patients with a history of thrombosis, abnormal bleeding profile, known hypersensitivity to TA or HQ, and endocrinal disease.","ALL","18 Years","40 Years",{"count":19,"type":20},45,"ESTIMATED","INTERVENTIONAL",[23],"NA","Melasma is a common acquired disorder of hyperpigmentaion caused by increased melanin production by melanocytes.\n\nMelasma is a name derived from the Greek word melas meaning black.It is characterized by the appearance of brownish or grayish symmetrical patches on sun-exposed skin, most commonly on the face. Compared to men, women are more likely to be affected.",[26],"Refractory Melasma","RECRUITING","2024-07-23",{"date":30,"type":31},"2024-07-26","ACTUAL",{"date":33,"type":31},"2024-06-01",{"date":35,"type":20},"2025-06-10",{"name":37,"class":38},"Egymedicalpedia","INDUSTRY",""]