[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"retinal-vascular\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:retinal-vascular":45},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":12,"acronym":4,"eligibilityCriteria":13,"healthyVolunteers":14,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":17,"targetDuration":4,"studyType":20,"phases":21,"briefSummary":23,"conditions":24,"keywords":26,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":5},"100418646",false,"NCT04731415","Physiologic Change of Posterior Ocular Segment During Pregnancy","Inclusion Criteria:\n\n* Healthy pregnant women\n* Age \\> 18 years\n* Gestational age \\\u003C 12 weeks\n* Written informed consent\n\nExclusion Criteria:\n\n* High risk pregnancy such as multifetal pregnancy and preeclampsia\n* History of vitreoretinal diseases such as retinal vasculitis\n* History of intraocular laser treatments or intraocular surgeries\n* History of systemic diseases such as diabetes mellitus and thyroid disease\n* Refractive error; spherical equivalence \\> 4 diopters\n* Clear ocular media\n* Could not be taken the images by non-dilated pupil\n\nWithdrawal Criteria:\n\n* Preterm labor; gestational age \\\u003C 34 weeks\n* Multifetal pregnancy was demonstrated by ultrasound\n* Severe labor and delivery complications such as\n* Severe postpartum complications such as postpartum bleeding\n* Taking hormone during the follow-up period",true,"FEMALE","18 Years",{"count":18,"type":19},69,"ESTIMATED","INTERVENTIONAL",[22],"NA","Women's physiology changes markedly during normal pregnancy. The most distinct alterations occur in the hormonal and cardiovascular systems. There is a dramatic increase in both estrogen and progesterone. Blood volume starts to increase in the first gestational period and reaches a peak in the third trimester.\n\nThe physiologic ocular changes during pregnancy are mainly the result of hormonal and blood volume increase, and then are usually marked in the third trimester.",[25],"Retinal Vascular",[27,28,29,30,31,32],"Retinal vascular density","Optical coherence tomography angiography","Choroidal thickness","Retinal nerve fiber layer thickness","Optic nerve head","Optical coherence tomography","NOT_YET_RECRUITING","2021-06-29",{"date":36,"type":37},"2021-06-30","ACTUAL",{"date":39,"type":19},"2021-07-01",{"date":41,"type":19},"2026-06-30",{"name":43,"class":44},"Khon Kaen University","OTHER",""]