[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"right-heart-catheterisation\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:right-heart-catheterisation":104},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,41,71],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":12,"acronym":4,"eligibilityCriteria":13,"healthyVolunteers":10,"sex":14,"minAge":15,"maxAge":4,"enrollmentInfo":16,"targetDuration":4,"studyType":19,"phases":4,"briefSummary":20,"conditions":21,"keywords":26,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":29,"lastUpdatePostDateStruct":30,"startDateStruct":33,"completionDateStruct":35,"leadSponsor":37,"locationsCount":40},"100643993",false,"NCT07667595","Correlation Between CT Pulmonary Angiography Metrics and Right Heart Catheterization Parameters in Pre-Capillary Pulmonary Hypertension","Inclusion Criteria:\n\n1-Age ≥ 18 years at time of enrolment. 2-Confirmed pre-capillary pulmonary hypertension on RHC performed at Assiut University Hospital: mPAP \\> 20 mmHg AND PAWP ≤ 15 mmHg AND PVR ≥ 2 Wood Units.\n\n3-WHO PH Clinical Group 1 (PAH), Group 3 (PH due to lung disease\u002Fhypoxia), or Group 4 (CTEPH \u002F chronic thromboembolic PH) classification assigned by the PH-MDT.\n\n4-Both CTPA and RHC performed within a maximum interval of 4 weeks. b. Exclusion criteria:\n\n1. WHO PH Group 2 (PH due to left heart disease) or Group 5 (PH with unclear\u002Fmultifactorial mechanisms) .\n2. Active malignancy.\n3. Pregnancy, confirmed or suspected.\n4. Contraindication to iodinated contrast agent: eGFR \\\u003C 30 mL\u002Fmin\u002F1.73m² OR documented history of severe anaphylactic contrast reaction.\n5. Inability to sustain breath-hold of ≥ 8 seconds (impairs CTPA quality).\n6. Initiation or dose escalation of pulmonary vasodilator therapy (endothelin receptor antagonist, PDE5 inhibitor, soluble guanylate cyclase stimulator, or prostanoid) in the interval between CTPA and RHC, or within 4 weeks prior to CTPA.\n7. Patient refusal to consent or inability to provide informed consent","ALL","18 Years",{"count":17,"type":18},60,"ESTIMATED","OBSERVATIONAL","Pulmonary hypertension (PH) is a hemodynamic and pathophysiological condition defined by a mean pulmonary artery pressure (mPAP) greater than 20 mmHg at rest, as confirmed by right heart catheterization (RHC) (1). The global prevalence of PH is estimated at approximately 1% of the adult population, rising to 10% or more in individuals over 65 years of age.Pre-capillary pulmonary hypertension, which includes pulmonary arterial hypertension (PAH) and chronic thromboembolic pulmonary hypertension (CTEPH), is characterized by a pulmonary arterial wedge pressure (PAWP) ≤15 mmHg and an elevated pulmonary vascular resistance (PVR) ≥2 Wood units (2)\n\nComputed tomography pulmonary angiography (CTPA) is routinely performed in the diagnostic workup of PH and offers a non invasive alternative that can generate multiple quantitative metrics from a single scan (3). Traditional CTPA metrics, including main pulmonary artery diameter (MPAd), the ratio of MPAd to ascending aortic diameter, central pulmonary arteries, and right ventricular to left ventricular diameter (RV\u002FLV ratio) were previously studied in PH patients (4,5,6) Most existing studies have evaluated CTPA metrics in isolation or within single PH subgroups, limiting generalizability across the broader pre-capillary PH population (7).\n\nTherefore, this study aims to systematically investigate the correlation between multiple quantitative CTPA metrics and key invasive hemodynamic parameters derived from RHC in patients with confirmed pre-capillary pulmonary hypertension",[22,23,24,25],"Pulmonary Hypertension","Precapillary Pulmonary Hypertension","Right Heart Catheterisation","CT Angiography",[27],"CTPA and RHC in precapillary PHTN","NOT_YET_RECRUITING","2026-06-24",{"date":31,"type":32},"2026-06-25","ACTUAL",{"date":34,"type":18},"2026-06-30",{"date":36,"type":18},"2026-07-30",{"name":38,"class":39},"Assiut University","OTHER",1,{"id":42,"slug":4,"hasResults":10,"nctId":43,"briefTitle":44,"officialTitle":45,"acronym":46,"eligibilityCriteria":47,"healthyVolunteers":10,"sex":14,"minAge":15,"maxAge":48,"enrollmentInfo":49,"targetDuration":4,"studyType":51,"phases":52,"briefSummary":54,"conditions":55,"keywords":58,"overallStatus":62,"whyStopped":4,"lastUpdateSubmitDate":29,"lastUpdatePostDateStruct":63,"startDateStruct":65,"completionDateStruct":67,"leadSponsor":69,"locationsCount":40},"100619508","NCT07345533","EXPLORATORY STUDY OF THE MYHEARTSENTINEL SYSTEM, A CARDIAMETRICS MEDICAL DEVICE","EXPLORATORY STUDY OF THE MYHEARTSENTINEL SYSTEM, A CARDIAMETRICS MEDICAL DEVICE - ANALYSIS OF CARDIAC ELECTROPHYSIOLOGICAL AND MECHANICAL SIGNALS DURING A DECOMPENSATION\u002FRECOMPENSATION EPISODE IN PATIENTS WITH HEART FAILURE IN THE HOSPITAL AND UPON DISCHARGE HOME","ASEMC-DR","Inclusion Criteria:\n\n* Patients aged between 18 and 90 years\n* Affiliated with the social security system.\n* Patients who have been informed of the study and have signed informed consent.\n* Patients with heart failure and one of the following two criteria:\n\n  * Hospitalized for hemodynamic assessment\n  * Hospitalized in a cardiology unit (ICU or telemetry unit) for congestive decompensation of known heart failure defined by \\[8\\] minimal dyspnea at rest or during exercise AND an elevation of BNP \\> 400 µg\u002Fml or NT-proBNP \\> 1600 µg\u002Fml\n\nExclusion Criteria:\n\n* Patient hospitalized for decompensated heart failure due to an infectious cause requiring antibiotic treatment\n* Patient requiring intravenous inotropes within the last 24 hours\n* Patient with ventricular arrhythmias or permanent AF\n* ACS with ST+ complex complicated by heart failure\n* Valvulopathy awaiting interventional management\n* Pericardial constriction\n* Pregnant or breastfeeding women\n* Women of childbearing potential without effective contraception\n* Patients under guardianship, curatorship, legal protection, or legal protection.\n* Patients already enrolled in an interventional clinical trial that may impact the electrophysiological and cardiac mechanical measurements of the medical device under study. • Inability to position the sensor on the thoracic area of interest\n* Patients with open wounds, recent scars, or skin infections at the intended SCOUT device placement site\n* Patients suffering from dermatitis, eczema, psoriasis, or other skin conditions at the placement site.\n* Physical or psychological inability of the patient or caregiver to use the digital medical telemonitoring device and\u002For its collection accessories, as determined by the physician wishing to include the patient in the medical telemonitoring project;\n* Patient refusal to transmit the data necessary to monitor the effective use of the DMN and to obtain individualized or national real-life usage results;\n* Patient refusal to receive therapeutic support.","90 Years",{"count":50,"type":18},70,"INTERVENTIONAL",[53],"NA","Background:\n\nChronic heart failure represents a major public health challenge, affecting approximately 64 million people worldwide and generating high costs in terms of mortality, frequent hospitalizations, and medical expenses. In France, this disease is expected to cause nearly 70,000 deaths and 181,000 hospital admissions in 2022. Current management, based on periodic consultations, fails to effectively prevent acute exacerbations, highlighting the importance of technological solutions such as remote monitoring.\n\nObjective:\n\nThis study aims to demonstrate the value of regular monitoring of electrophysiological and mechanical cardiac signals and parameters in patients with chronic heart failure. Its goal is to build a database of signals from an external measuring device (MyHeartSentinel MHS) to identify parameters that evolve in relation to biological and\u002For hemodynamic changes and\u002For the patient's clinical status. The results of this study will enable the further development of an automated monitoring solution for heart failure patients to enable early detection and management of decompensation.\n\nMaterials and Methods:\n\nA total of 70 patients diagnosed with chronic heart failure will be included, including 30 patients hospitalized for heart failure decompensation and 40 patients hospitalized for hemodynamic assessment. Electrophysiological and cardiac mechanical data will be collected using a skin-based measuring device. These data will then be correlated with biological and\u002For hemodynamic changes and\u002For the patient's clinical status. They will contribute to the training of an algorithm to detect the risk of decompensation.\n\nHypothesis Tested:\n\nAbility of MHS to detect electrophysiological and cardiac mechanical data related to cardiac decompensation, such as cardiac filling pressure.",[56,57,24],"Heart Failure","Telemonitoring",[57,59,60,61],"heart failure","right heart catheterisation","acute heart failure","RECRUITING",{"date":64,"type":32},"2026-06-26",{"date":66,"type":32},"2025-07-17",{"date":68,"type":18},"2028-03-17",{"name":70,"class":39},"University Hospital, Caen",{"id":72,"slug":4,"hasResults":10,"nctId":73,"briefTitle":74,"officialTitle":74,"acronym":4,"eligibilityCriteria":75,"healthyVolunteers":10,"sex":14,"minAge":15,"maxAge":4,"enrollmentInfo":76,"targetDuration":4,"studyType":19,"phases":4,"briefSummary":78,"conditions":79,"keywords":81,"overallStatus":62,"whyStopped":4,"lastUpdateSubmitDate":94,"lastUpdatePostDateStruct":95,"startDateStruct":97,"completionDateStruct":99,"leadSponsor":101,"locationsCount":103},"100603495","NCT07137260","Digital Assessment of Real-World Walking Activity in Pulmonary Hypertension: A Prospective Multicenter Trial","Inclusion Criteria:\n\n* Pulmonary hypertension confirmed by right heart catheterization\n* Presence of precapillary pulmonary hypertension at time of recruitment, defined as mean pulmonary arterial pressure (MAP) ≥ 20 mmHg, pulmonary arterial wedge pressure (PAWP) ≤ 15 mmHg and pulmonary vascular resistance (PVR) \\> 2 Wood units (160 dyn·s·cm-5)\n* After the right heart catheterization another follow-up visit is required in 3, 6, or 12 months\n* Independent walking without assistance and a 6-min walking distance \\> 100m\n* WHO Functional Class I-III\n* Ability to provide informed consent and to participate in the study procedures\n* Willingness to wear the Axivity AX6 Sensor for 7 days\n\nExclusion Criteria:\n\n* Hospitalization for a pulmonological disease within the 30 days prior to study recruitment\n* Neurological or orthopedic disease which limits walking ability\n* Acute pain which limits walking ability\n* Poor vision, which limits walking ability\n* Terminal illness with life expectancy \\\u003C 1 year\n* Ongoing treatment for malignancy\n* Acute psychosis or other severe psychiatric illness\n* Substance dependence",{"count":77,"type":18},77,"The goal of this observational study is to validate digital mobility outcomes for monitoring the treatment and disease progression in adult patients with pulmonary hypertension. The main question it aims to answer is:\n\n-Do digital mobility outcomes (measured digital endpoints characterizing walking behavior) correlate with measures of precapillary pulmonary pressure as assessed by right heart catheterization?\n\nParticipants will be asked to wear a small sensor on the lower back for one week at a time for a total of 3 times: at diagnosis and follow-up visits at 3-6 months and again at 6-12 months. Follow-up visits are scheduled by the treating clinician. At the end of the study participants can choose to receive feedback on the sensor measurements.",[22,23,24,80],"Digital Mobility Outcomes",[82,83,84,85,86,87,88,89,90,91,92,93],"Digital mobility assessment","Right heart catheterization","Mobility assessment","Digital mobility outcome","Pulmonary hypertension","Pulmonary arterial hypertension","Sensor","Axivity sensor","Precapillary pulmonary hypertension","Walking assessment","Walking test","Physical activity","2025-08-15",{"date":96,"type":32},"2025-08-22",{"date":98,"type":32},"2024-04-19",{"date":100,"type":18},"2027-04",{"name":102,"class":39},"Simon Jäger",4,""]