[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"sickle-cells-disease\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:sickle-cells-disease":42},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":10,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":25,"conditions":26,"keywords":28,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":31,"lastUpdatePostDateStruct":32,"startDateStruct":35,"completionDateStruct":37,"leadSponsor":39,"locationsCount":5},"100374548",false,"NCT04156893","RH Genotype Matched RBC Transfusions","RH Genotype Matched Red Cell Transfusions for Patients With Sickle Cell Disease","RBC","Inclusion Criteria:\n\n* Subjects age \\>6 months\n* Diagnosis of SCD, all genotypes\n* Require a period of chronic red cell transfusion therapy\n* Subject\u002Fparental\u002Fguardian permission (informed consent) and if appropriate, child assent\n\nExclusion Criteria:\n\n* Rare RH genotype that would preclude identification of sufficient RBC units\n* Antigen negative requirements due to alloimmunization that would preclude identification of sufficient RBC units\n* Alloimmunized to D antigen\n* Rh alloimmunized patients for whom providing RH genotype matched blood would expose the patient to an antigen that would not be consistent with standard of care and blood bank protocols\n* Parents\u002Fguardians or subjects who, in the opinion of the Investigator, may be non-compliant with study schedules or procedures","ALL","6 Months",{"count":19,"type":20},35,"ESTIMATED","INTERVENTIONAL",[23,24],"PHASE1","PHASE2","To determine the feasibility and efficacy of matching donor red cells by RH genotype for a cohort of chronically transfused patients with SCD.",[27],"Sickle Cells Disease",[29],"Chronic Transfusion","RECRUITING","2026-04-24",{"date":33,"type":34},"2026-04-27","ACTUAL",{"date":36,"type":34},"2020-01-30",{"date":38,"type":20},"2029-10",{"name":40,"class":41},"Children's Hospital of Philadelphia","OTHER",""]