[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"skin-massage\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:skin-massage":51},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":29,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":40,"lastUpdatePostDateStruct":41,"startDateStruct":44,"completionDateStruct":46,"leadSponsor":48,"locationsCount":5},"100610526",false,"NCT07228728","Exploring the Cutaneous Immune Response to Skin Massage in Early Life","A Randomised Controlled Trial to Investigate How Regular Skin Massage Impacts the Immune System in Early Life","CUTIE","Inclusion Criteria:\n\n1. Healthy babies born at term up to 6 months old\n2. Ability of parents\u002Fguardians\u002Fcaregivers to provide written informed consent for study participation\n3. Willingness of parents\u002Fguardians\u002Fcaregivers to comply with all study requirements.\n\nExclusion Criteria:\n\n1. Parents\u002Fguardians\u002Fcaregivers unable to give informed consent.\n2. Personal history of inflammatory skin disease (in particular atopic dermatitis)\n3. Active involvement in another interventional research study",true,"ALL","0 Months","6 Months",{"count":21,"type":22},109,"ESTIMATED","INTERVENTIONAL",[25],"NA","This project aims to study whether regular skin massage in babies induces cutaneous inflammation and whether this inflammatory response is amplified in those receiving daily (vs bi-weekly or no) skin massage over an 8 week period. Specifically, it aims to:\n\n1. Establish if massage increases \u002Fdecreases immune signals in the skin.\n2. Clarify if the effects of massage are enhanced with the frequency of massage. 3.) Assess changes in skin biology as a consequence of skin massage. 4.) Determine if massage impacts skin barrier function in the early years of life.",[28],"Skin Massage",[30,31,32,33,34,35,36,37,38],"Massage","Early life","dermatology","Immune System","Immune Response","Infant Development","Skin barrier","Microbiome","Interstitial Skin fluid","RECRUITING","2026-02-09",{"date":42,"type":43},"2026-02-11","ACTUAL",{"date":45,"type":43},"2026-01-02",{"date":47,"type":22},"2027-04-30",{"name":49,"class":50},"King's College London","OTHER",""]