Squamous Cell Carcinoma Of The Lung

2

Review clinical trials related to Squamous Cell Carcinoma Of The Lung. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

A Study Evaluating the Safety, Efficacy, and Pharmacokinetics (PK) of EVOLVE104 in Participants With Advanced Urothelial and Squamous Cell Carcinomas

The goal of this study is to evaluate the safety and effectiveness of EVOLVE104 in participants with advanced urothelial and squamous cell carcinomas who have previously taken standard treatment options, have declined or have been ineligible for treatment with these medications. Participants with advanced or metastatic cancer who meet all eligibility criteria may be eligible to participate in the study.

Participants needed: 160
Trial details
Phase: Phase 1Age: 18+Biological sex: AllType: InterventionalSponsor: EvolveImmune United, IncUpdated: Jul 2, 2026Locations: 12
Eligibility criteria

Participant must have documented disease progression during or post treatment wi... [+6]

The participant is a candidate for treatment with a targeted agent known to prov... [+12]

Status: Recruiting

Study of Safety and Tolerability of BCA101 Monotherapy and in Combination Therapy in Patients With EGFR-driven Advanced Solid Tumors

The investigational drug to be studied in this protocol, BCA101, is a first-in-class compound that targets both EGFR with TGFβ. Based on preclinical data, this bifunctional antibody may exert synergistic activity in patients with EGFR-driven tumors.

Participants needed: 292
Trial details
Phase: Phase 1Age: 18+Biological sex: AllType: InterventionalSponsor: Bicara TherapeuticsUpdated: Aug 15, 2025Locations: 20
Eligibility criteria

Patient must have measurable disease amendable to biopsy and be willing to under... [+5]

For Part A: Exposure to anti-EGFR antibodies within 4 weeks of the first dose of... [+8]