[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"stoma-closure\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:stoma-closure":46},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":10,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":29,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":4},"100636916",false,"NCT07571902","Revised-Paravertebral Nerve Blocks for Enhanced Recovery After Stoma Closure","Revised-Paravertebral Nerve Blocks for Enhanced Recovery After Stoma Closure: A Randomized Clinical Trial","r-PVB III","Inclusion Criteria:\n\n* Adults aged 18 years or older.\n* Patients scheduled to undergo elective ileostomy, colostomy, or ileocolostomy reversal surgery.\n\nExclusion Criteria:\n\n* Contraindications to nerve block, including skin infection at the puncture site, increased intracranial pressure, uncorrectable coagulopathy, bridging indication for therapeutic anticoagulation (CHADS-VASc ≥8), sepsis, or allergy to local anesthetics.\n* Expected operative time longer than 150 minutes, or stoma reversal not being the primary surgical procedure.\n* Chronic opioid use.\n* Heart failure, liver failure, renal failure, coagulation disorders, or a history of allergy to local anesthetics.\n* Inability to comply with study procedures, including severe psychiatric illness, refusal to sign informed consent, or anticipated difficulty in completing postoperative follow-up.","ALL","18 Years",{"count":19,"type":20},250,"ESTIMATED","INTERVENTIONAL",[23],"NA","After stoma closure, pain remains an important problem affecting patient recovery. A revised paravertebral block (r-PVB) was developed as a single-shot, large-volume intercostal-space injection performed at the exposed mid-axillary ninth to eleventh intercostal level with the patient kept supine after induction of anesthesia. Rather than puncturing the classical paraspinal target near the transverse process with the patient in a prone or lateral position, the r-PVB technique is designed to exploit retrograde spread of local anesthetic from the intercostal space to the paravertebral space, thereby generating a functional paravertebral block while avoiding direct entry into the paravertebral space and the need for specific body positioning. The r-PVB technique addresses several practical limitations of conventional PVB by eliminating the need to reposition an anesthetized patient, using a more accessible and potentially clearer sonographic window, reducing interference from transverse-process shadowing, and facilitating in-plane needle visualization.",[26,27,28],"Stoma Closure","Postoperative Pain","Quality of Recovery",[26,30,31,27,28,32,33],"Ileostomy Closure","Colostomy Closure","Intercostal Space Block","Paravertebral Nerve Block","NOT_YET_RECRUITING","2026-05-06",{"date":37,"type":38},"2026-05-11","ACTUAL",{"date":40,"type":20},"2026-04-27",{"date":42,"type":20},"2027-12-31",{"name":44,"class":45},"Sixth Affiliated Hospital, Sun Yat-sen University","OTHER",""]