[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"symptomatic-severe-aortic-stenosis\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:symptomatic-severe-aortic-stenosis":41},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":10,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":29,"lastUpdatePostDateStruct":30,"startDateStruct":33,"completionDateStruct":35,"leadSponsor":37,"locationsCount":40},"100582288",false,"NCT06861361","Surgical vs Transcatheter Aortic Valve Replacement in YOUNG Patients","Surgical Bioprosthesis Aortic Valve Replacement Vs. Myval Balloon-Expandable THV Series in Patients Aged 65 to 75 With Symptomatic Severe Aortic Stenosis Judged Eligible by Heart Team","START YOUNG","Inclusion Criteria:\n\nParticipant will be included if all the following criteria are met:\n\n1. Patients aged ≥65 and ≤75\n2. Symptomatic severe aortic stenosis (mean gradient≥40mmHg, and or peak velocity\\>4m\u002Fsec).\n3. Patients with symptomatic heart disease due to severe native calcific aortic stenosis, as judged by a multidisciplinary heart team (including a cardiac surgeon), for whom SAVR or transfemoral TAVR is deemed feasible and approved by the local heart team.Signed informed consent for participation in the clinical investigation\n\nExclusion Criteria:\n\nParticipant will not be included if any one of the following conditions exists:\n\n1. Unable to understand and follow clinical investigation-related instructions or unable to comply with the clinical investigation protocol\n2. Life expectancy less than 1 year\n3. Known hypersensitivity or allergy to aspirin, clopidogrel or any Device frame components.\n4. Under judicial protection, tutorship, or curatorship\n5. Participation in another trial before the primary endpoint","ALL","65 Years","75 Years",{"count":20,"type":21},1180,"ESTIMATED","INTERVENTIONAL",[24],"NA","The study objective is to demonstrate that the clinical outcomes of the Myval balloon-expandable THV series are non-inferior to those of SAVR in patients with symptomatic severe aortic stenosis aged 65 to 75 years.",[27],"Symptomatic Severe Aortic Stenosis","RECRUITING","2026-05-07",{"date":31,"type":32},"2026-05-12","ACTUAL",{"date":34,"type":32},"2025-05-15",{"date":36,"type":21},"2037-09",{"name":38,"class":39},"Ceric Sàrl","INDUSTRY",49,""]