[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"threaten-preterm\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:threaten-preterm":47},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":12,"acronym":4,"eligibilityCriteria":13,"healthyVolunteers":14,"sex":15,"minAge":16,"maxAge":17,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":29,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":4},"100619395",false,"NCT07344064","The Effects of Adjunctive Therapy With Vaginal Tablets Lactobacillus Acidophilus and a Low Dose Estriol (Gynoflor®) to Prolong Pregnancy Time in Preterm Labor, A Randomized Controlled Trial","Inclusion Criteria\n\n\\- Pregnant women diagnosed with preterm labor or threatened preterm labor, with a gestational age between 24 and 33 weeks, who are receiving tocolytic therapy.\n\nExclusion Criteria\n\n* Age under 18 years or 35 years and older\n* Incomplete course of Gynoflor® (less than 6 days of use)\n* Presence of contraindications to tocolysis\n* Preterm premature rupture of membranes (PPROM)\n* Unable to be contacted for follow-up\n* History of allergy to probiotics or Gynoflor®\n* Multiple gestation\n* History of short cervix diagnosed between 16-24 weeks of gestation\n* History of previous preterm labor (PTL)\n* Pregnancy achieved via assisted reproductive technology (ART)\n* Presence of fetal anomaly\n* History of antepartum hemorrhage\n* Substance abuse, including cigarette smoking, alcohol, cocaine, or heroin use\n* Other causes of preterm labor such as uterine overdistension (e.g., polyhydramnios, multifetal gestation), uterine abnormalities (e.g., myoma uteri), or systemic infections, except vaginitis",true,"FEMALE","18 Years","35 Years",{"count":19,"type":20},80,"ESTIMATED","INTERVENTIONAL",[23],"NA","The study aim to study The Adjunctive therapy with vaginal tablets containing Lactobacillus acidophilus KS400 and low-dose Estriol (Gynoflor®) in addition to standard tocolytic treatment administered once daily for 6 days starting the same day as tocolytic therapy, in pregnant women diagnosed with preterm labor at gestational age 24-33 weeks .Primary Outcome is the rate of pregnancy prolongation beyond 7 days after initiation of tocolytic therapy.",[26,27,28],"Threaten Preterm","Prethrem Labour","Bacterial Vaginitis",[30,31,32,33,34],"Lactobacillus","Gynoflor","Threaten preterm","Bacterial vaginitis","Probiotic","NOT_YET_RECRUITING","2026-01-07",{"date":38,"type":39},"2026-01-15","ACTUAL",{"date":41,"type":20},"2026-02",{"date":43,"type":20},"2026-10",{"name":45,"class":46},"Queen Savang Vadhana Memorial Hospital, Thailand","OTHER",""]