[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"tibial-plateau-fracture\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:tibial-plateau-fracture":59},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":10,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":13,"conditions":24,"keywords":34,"overallStatus":46,"whyStopped":4,"lastUpdateSubmitDate":47,"lastUpdatePostDateStruct":48,"startDateStruct":51,"completionDateStruct":53,"leadSponsor":55,"locationsCount":58},"100593309",false,"NCT07004764","Enhancing Wound Perfusion in High-Risk Lower Extremity Orthopaedic Surgery: A Study on Nitropaste Using Intraoperative SPY Imaging.","Enhancing Wound Perfusion in High-Risk Lower Extremity Orthopaedic Surgery: A Feasibility Study on Nitropaste Using Intraoperative SPY Imaging.","SPY NITROPASTE","Inclusion Criteria:\n\n* Adults aged 18 years or older.\n* Undergoing surgery for one of the following procedures:\n\n  * Current Procedural Terminology (CPT) 28415 - Open reduction calcaneal fracture ± internal\u002Fexternal fixation\n  * CPT-27814 - Open reduction of bimalleolar fracture ± internal\u002Fexternal fixation\n  * CPT-27822 - Open reduction trimalleolar ankle fracture, medial and lateral malleoli only, ± internal\u002Fexternal fix\n  * CPT-27823 - Open reduction trimalleolar ankle fracture, including posterior malleolus, ± internal\u002Fexternal fix\n  * CPT-27826 - Open reduction pilon fracture, internal\u002Fexternal fixation of fibula ONLY\n  * CPT-27827 - Open reduction pilon fracture, internal\u002Fexternal fixation of tibia ONLY\n  * CPT-27828 - Open reduction pilon fracture, internal\u002Fexternal fixation of tibia AND fibula\n  * CPT-27535 - Open reduction unicondylar tibial plateau fracture, ± internal\u002Fexternal fixation\n  * CPT-27536 - Open reduction bicondylar tibial plateau fracture, ± internal\u002Fexternal fixation\n  * CPT-28445 - Open reduction of talus fracture, ± internal\u002Fexternal fixation\n  * CPT-27650 - Primary Achilles tendon repair\n* English-speaking\n* Able to provide informed consent during preoperative clinic visit, in the preoperative nursing area, or on inpatient units.\n\nExclusion Criteria:\n\n* Contraindications to nitroglycerin, including known allergy.\n* Allergy to indocyanine green or components of ICG dye, including allergies to iodine or shell-fish.\n* Severe kidney injury, as determined by attending surgeon and\u002For anesthesiologist, that would impair clearance of ICG dye.\n* Pregnant patients","ALL","18 Years",{"count":19,"type":20},15,"ESTIMATED","INTERVENTIONAL",[23],"PHASE1",[25,26,27,28,29,30,31,32,33],"Achilles Tendon Repairs\u002FReconstructions","Pilon Fracture of Tibia","Tibial Plateau Fracture","Ankle Fracture (Bimalleolar Equivalent, Bimalleolar, or Trimalleolar)","Calcaneus Fractures","Talus Fracture","Wound Infection Deep","Wound Infection Post-Traumatic","Wound Dehiscence, Surgical",[35,36,37,38,39,26,27,40,29,41,42,43,44,45],"Laser-assisted indocyanine green angiography","nitropaste","nitroglycerin","topical nitroglycerin","Achilles tendon repairs\u002Freconstructions","Ankle Fracture (bimalleolar equivalent, bimalleolar, or trimalleolar)","Talus fracture","Wound Dehiscence","Wound infection","tissue perfusion","Orthopaedic surgery","NOT_YET_RECRUITING","2026-03-30",{"date":49,"type":50},"2026-03-31","ACTUAL",{"date":52,"type":20},"2026-11",{"date":54,"type":20},"2027-12",{"name":56,"class":57},"Johns Hopkins University","OTHER",2,""]