[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"transperineal-cryoablation\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:transperineal-cryoablation":44},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":10,"sex":15,"minAge":16,"maxAge":17,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":28,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":5},"100636541",false,"NCT07567027","Improving Cryoablation Efficacy With BARRigel Rectal Spacing (ICE-BARR)","Improving Cryoablation Efficacy With BARRigel Rectal Spacing (ICE-BARR) Trial","Inclusion Criteria:\n\n* Male patients aged 40-95 years.\n* Biopsy-confirmed localized prostate cancer (Grade Group ≥ 2). Salvage cryoablation cases may be included.\n* Unifocal disease visible on multiparametric MRI (mpMRI) and amenable to focal or whole gland cryoablation.\n* Prostate-specific antigen (PSA) \\\u003C 20 ng\u002Fml.\n* No metastatic disease on Prostate-Specific Membrane Antigen (PSMA) PET\u002FCT, when recommended per National Comprehensive Cancer Network (NCCN) guidelines.\n* Eligible for and consenting to transperineal cryoablation under anesthesia.\n* Willingness to comply with post-procedure follow-up, including PSA testing and imaging.\n* Cryoablation which requires treatment of the posterior prostate as per clinician judgement.\n\nExclusion Criteria:\n\n* Evidence of metastatic disease.\n* Prior radiation therapy to the area of the prostate.\n* Active rectal or urinary tract infection.\n* Known allergy to hyaluronic acid products or contrast agents.\n* Inability to tolerate MRI.\n* Inability or unwillingness to comply with study follow-up.","MALE","40 Years","95 Years",{"count":19,"type":20},20,"ESTIMATED","INTERVENTIONAL",[23],"NA","The purpose of this study is to evaluate the feasibility, safety, and potential protective benefit of Barrigel, a hyaluronic acid-based rectal spacer, in patients undergoing prostate cryoablation for localized or recurrent prostate cancer. The primary aim is to assess Barrigel thermal stability during cryoablation.",[26,27],"Prostate Cancer (Diagnosis)","Transperineal Cryoablation",[29,30,31],"cryoablation","prostate","Barrigel","NOT_YET_RECRUITING","2026-04-28",{"date":35,"type":36},"2026-05-05","ACTUAL",{"date":38,"type":20},"2026-06-01",{"date":40,"type":20},"2028-06-01",{"name":42,"class":43},"NYU Langone Health","OTHER",""]