Variant Restless Legs Syndrome

1

Review clinical trials related to Variant Restless Legs Syndrome. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Novel Calcium Channel Modulators in RLS and Variants: Efficacy & Safety

The goal of this \[study type: clinical trial\] is to \[primary purpose: evaluate the efficacy and safety of a novel calcium channel modulator in treating Restless Legs Syndrome (RLS) and its variant subtypes\] in \[describe participant population/primary condition: adult patients aged 18-75 years with confirmed RLS or its variant subtypes, who meet the study's eligibility criteria\]. The main question\[s\] it aims to answer \[is/are\]: * Does the novel calcium channel modulator improve RLS-related symptoms (assessed by the International Restless Legs Syndrome Study Group Rating Scale, IRLS) after the treatment period? * What is the safety profile (incidence of adverse events) of this calcium channel modulator in RLS patients? Participants will \[describe the main tasks participants will be asked to do, interventions they'll be given\]: * Receive oral administration of the novel calcium channel modulator (40mg twice daily) for 12 consecutive weeks * Complete scheduled follow-up visits for symptom assessments, safety monitoring, and questionnaire completion

Participants needed: 20
Trial details
Phase: Phase 1Age: 18-75Biological sex: AllType: InterventionalSponsor: Beijing Friendship HospitalUpdated: Mar 6, 2026Locations: 1
Eligibility criteria

1. Aged 18-75 years, regardless of gender. [+3]

1. Secondary RLS (e.g., iron deficiency anemia with serum ferritin <30μg/L, rena... [+7]