[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"vascular-endothelial-function\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:vascular-endothelial-function":64},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,46],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":15,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":29,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":45},"100512002",false,"NCT05946785","Oxidative Stress in Microvascular Dysfunction Following Gestational Diabetes","Role of Oxidative Stress in Microvascular Dysfunction Following Gestational Diabetes","INCLUSION CRITERIA:\n\n* female sex\n* 18 -50 years old\n* pregnancy history within 5 years of the study visit\n* had gestational diabetes diagnosed by their obstetrician and confirmed according to the American College of Obstetricians and Gynecologists criteria for gestational diabetes\n* or without a history of gestational diabetes\n\nEXCLUSION CRITERIA:\n\n* skin diseases\n* current tobacco\u002Fe-cigarette use\n* diagnosed or suspected hepatic or metabolic disease including diabetes\n* statin or other cholesterol-lowering medication\n* current antihypertensive medication\n* history of preeclampsia or gestational hypertension\n* current pregnancy\n* body mass index \\\u003C18.5 kg\u002Fm2\n* allergy to materials used during the experiment.(e.g. latex), known allergies to study drugs.",true,"FEMALE","18 Years","50 Years",{"count":20,"type":21},28,"ESTIMATED","INTERVENTIONAL",[24],"EARLY_PHASE1","The purpose of this investigation is to examine the role of oxidative stress in aberrant microvascular function in otherwise healthy women with a history of GDM.",[27,28],"Gestational Diabetes","Vascular Endothelial Function",[30,31,32],"gestational diabetes","postpartum","vascular","RECRUITING","2025-05-07",{"date":36,"type":37},"2025-05-13","ACTUAL",{"date":39,"type":37},"2023-07-01",{"date":41,"type":21},"2027-06-01",{"name":43,"class":44},"Anna Stanhewicz, PhD","OTHER",1,{"id":47,"slug":4,"hasResults":10,"nctId":48,"briefTitle":49,"officialTitle":49,"acronym":4,"eligibilityCriteria":50,"healthyVolunteers":15,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":51,"targetDuration":4,"studyType":22,"phases":53,"briefSummary":54,"conditions":55,"keywords":57,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":58,"startDateStruct":59,"completionDateStruct":61,"leadSponsor":63,"locationsCount":45},"100512003","NCT05946798","Role of NADPH Oxidase in Microvascular Dysfunction Following GDM","INCLUSION CRITERIA:\n\n* 18 years or older\n* pregnant within 5 years of the study visit\n* had gestational diabetes diagnosed by their obstetrician and confirmed according to the American College of Obstetricians and Gynecologists criteria for gestational diabetes.\n* or without a history of gestational diabetes\n\nEXCLUSION CRITERIA:\n\n* skin diseases\n* current tobacco or electronic cigarette\u002Fvape pen use,\n* diagnosed or suspected hepatic or metabolic disease including diabetes,\n* statin or other cholesterol-lowering medication,\n* current antihypertensive medication,\n* history of preeclampsia or gestational hypertension,\n* current pregnancy,\n* body mass index \\\u003C18.5 kg\u002Fm2,\n* allergy to materials used during the experiment.(e.g. latex),\n* known allergies to study drugs",{"count":52,"type":21},40,[24],"The purpose of this investigation is to examine NADPH oxidase as a source of reactive oxygen species contributing to aberrant microvascular function in otherwise healthy women with a history of GDM.",[27,56,28],"Oxidative Stress",[30,31,32],{"date":36,"type":37},{"date":60,"type":37},"2023-08-30",{"date":62,"type":21},"2028-06-01",{"name":43,"class":44},""]