Clinical trials

9

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

KC1036 in Combination With PD-1 Antibody and Platinum-based Chemotherapy for First-line Advanced Esophageal Cancer

The purpose of this study is to evaluate the efficacy and safety of KC1036 in combination with PD-1 antibody and platinum-based chemotherapy as a first-line treatment for patients with unresectable locally advanced, recurrent, or metastatic esophageal squamous cell carcinoma (ESCC).

Participants needed: 60
Trial details
Phase: Phase 2Age: 18-75Biological sex: AllType: InterventionalSponsor: Beijing Konruns Pharmaceutical Co., Ltd.Updated: Mar 20, 2026Locations: 1
Eligibility criteria

Males or females aged 18 to 75 years; [+9]

Symptomatic, untreated, or actively progressing central nervous system (CNS) met... [+13]

Status: Not yet recruiting

A Study of KC1086 in Patients With Advanced Solid Tumors

The purpose of this study is to evaluate the safety,tolerability, pharmacokinetics, and preliminary efficacy of KC1086 in participants with advanced recurrent or metastatic solid tumors. The trial will be divided into two parts: dose-escalation phase and dose-expansion phase.

Participants needed: 66
Trial details
Phase: Phase 1Age: 18+Biological sex: AllType: InterventionalSponsor: Beijing Konruns Pharmaceutical Co., Ltd.Updated: Aug 12, 2025
Eligibility criteria

Histologically or cytologically confirmed recurrent or metastatic solid tumors; [+6]

Any patient who is known to have untreated central nervous system (CNS) metastas... [+14]

Status: Recruiting

A Study of Jincaopian Tablets on Chronic Pelvic Pain After Pelvic Inflammatory Disease

The objective of this phase III trial to evaluate the efficacy and safety of Jincaopian Tablets in the treatment of subjects with chronic pelvic pain after pelvic inflammatory disease

Participants needed: 414
Trial details
Phase: Phase 3Age: 18-50Biological sex: FemaleType: InterventionalSponsor: Beijing Konruns Pharmaceutical Co., Ltd.Updated: Oct 17, 2024Locations: 1
Eligibility criteria

Meet the diagnostic criteria for chronic pelvic pain sequelae of pelvic inflamma... [+4]

Pelvic inflammatory disease (acute attack); [+14]

Status: Recruiting

A Study of KC1036 in Patients with Advanced Thymic Tumors

This is a single arm,open-label, multicentric, phase II study to evaluate the efficacy and safety of KC1036 in patients with advanced recurrent or metastatic thymoma or thymic carcinoma.

Participants needed: 30
Trial details
Phase: Phase 2Age: 18-75Biological sex: AllType: InterventionalSponsor: Beijing Konruns Pharmaceutical Co., Ltd.Updated: Oct 17, 2024Locations: 2
Eligibility criteria

Patients with thymoma or thymic carcinoma confirmed by cytologically or histolog... [+7]

Patients with thymus neuroendocrine tumors; [+17]

Status: Recruiting

To Evaluate KC1036 in the Patients with Advanced Digestive System Tumors

The purpose of this study is to evaluate the preliminary efficacy, safety, tolerability and pharmacokinetics of KC1036 in participants with advanced recurrent or metastatic digestive system tumors.

Participants needed: 133
Trial details
Phase: Phase 1, Phase 2Age: 18-75Biological sex: AllType: InterventionalSponsor: Beijing Konruns Pharmaceutical Co., Ltd.Updated: Oct 17, 2024Locations: 13
Eligibility criteria

Histologically or cytologically confirmed malignant digestive system tumors; [+6]

Any patient who is known to have central nervous system (CNS) metastasis with cl... [+13]

Status: Recruiting

A Study of KC1036 in Patients with Advanced Solid Tumors

The purpose of this study is to evaluate the safety,tolerability, pharmacokinetics, and preliminary efficacy of KC1036 in participants with advanced recurrent or metastatic solid tumors. The trial will be divided into three parts: dose-escalation phase, dose-expansion phase, RP2D-extension phase.

Participants needed: 207
Trial details
Phase: Phase 1Age: 18+Biological sex: AllType: InterventionalSponsor: Beijing Konruns Pharmaceutical Co., Ltd.Updated: Oct 17, 2024Locations: 3
Eligibility criteria

Histologically or cytologically confirmed recurrent or metastatic solid tumors; [+4]

Untreated brain metastases or symptoms of brain metastases cannot be controlled... [+17]

Status: Recruiting

A Phase 1 Study of CX1003 (Kanitinib) in Patients with Advanced Solid Tumors

CX1003 is a novel multi-target tyrosine kinase inhibitor that is designed to primarily inhibit vascular endothelial growth factor receptor 2 (VEGFR2) and hepatocyte growth factor receptor (HGFR/MET). This study aimed to evaluate the safety, pharmacokinetics, and antitumor activity of CX1003 in patients with refractory advanced or metastatic solid tumors.

Participants needed: 126
Trial details
Phase: Phase 1Age: 18+Biological sex: AllType: InterventionalSponsor: Beijing Konruns Pharmaceutical Co., Ltd.Updated: Oct 17, 2024Locations: 1
Eligibility criteria

Histologically or cytologically confirmed recurrent or metastatic solid tumors; [+4]

Untreated brain metastases or symptoms of brain metastases cannot be controlled... [+12]

Status: Recruiting

A Study of KC1036 in Adolescents With Advanced Ewing Sarcoma

This open-label, single-arm clinical trial is to evaluate the safety and effectiveness of KC1036 in treating adolescents aged 12 and above with advanced Ewing sarcoma. Participants will take KC1036 once daily, with each treatment cycle lasting 4 weeks.

Participants needed: 30
Trial details
Phase: Phase 2Age: 12-18Biological sex: AllType: InterventionalSponsor: Beijing Konruns Pharmaceutical Co., Ltd.Updated: Aug 23, 2024Locations: 1
Eligibility criteria

Age between 12 and less than 18 years; [+9]

Patients with primary central nervous system tumors; [+16]

Status: Recruiting

A Study of KC1036 Versus Investigator's Choice of Chemotherapy in Patients With Advanced Esophageal Cancer

The purpose of this study is to evaluate the efficacy and safety of KC1036 versus investigator's choice of chemotherapy in patients with advanced recurrent or metastatic esophageal squamous cell carcinoma

Participants needed: 490
Trial details
Phase: Phase 3Age: 18-75Biological sex: AllType: InterventionalSponsor: Beijing Konruns Pharmaceutical Co., Ltd.Updated: Mar 7, 2024Locations: 1
Eligibility criteria

Males or females aged 18 to 75 years; [+9]

Any patient who is known to have untreated central nervous system (CNS) metastas... [+13]