Clinical trials

2

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

A Phase 1 Study of the Safety and Tolerability of CTX-10726

This is a Phase 1, open-label, first-in-human study of CTX-10726 monotherapy in patients with metastatic or locally advanced malignancies. The study will be conducted in 2 Cohorts: Cohort 1 Dose Escalation and Cohort 2 Dose Expansion.

Participants needed: 70
Trial details
Phase: Phase 1Age: 18+Biological sex: AllType: InterventionalSponsor: Compass TherapeuticsUpdated: Jun 5, 2026Locations: 5
Eligibility criteria

Age 18 years or older. [+17]

Developed clinically significant adverse reaction to prior PD-1 or PD-L1 therapy... [+23]

Status: Recruiting

A Phase 1 of CTX-8371 in Patients With Advanced Malignancies

This is a Phase 1, open-label, first-in-human study of CTX-8371 administered as a monotherapy in patients with metastatic or locally advanced malignancies. The study will be conducted in 2 cohorts: Dose Escalation and Dose Expansion.

Participants needed: 85
Trial details
Phase: Phase 1Age: 18+Biological sex: AllType: InterventionalSponsor: Compass TherapeuticsUpdated: Apr 20, 2026Locations: 9
Eligibility criteria

Age 18 years or older [+41]

Developed clinically significant adverse reaction to PD-1 or PD-L1 therapy, incl... [+9]