Clinical trials

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Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

A Study of DR-01 in Subjects With Large Granular Lymphocytic Leukemia or Cytotoxic Lymphomas

This is a multicenter, first-in-human, Phase 1/2 study to evaluate the safety, tolerability, pharmacokinetics, pharmacodynamics, and anti-tumor activity of DR-01 in adult patients with large granular lymphocytic leukemia or cytotoxic lymphomas

Participants needed: 200
Trial details
Phase: Phase 1, Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: Dren BioUpdated: Jun 17, 2026Locations: 37
Eligibility criteria

≥18 years of age. [+13]

A reactive LGL lymphocytosis to a viral infection or LGL associated with myelody... [+14]

Status: Available

Availability of Dibotatug (DR-01) Outside Clinical Trials Via Expanded Access for Eligible Participants

This is an expanded access program (EAP) for eligible participants designed to provide access to Dibotatug (DR-01). Physician-requested expanded access will generally only be considered for patients not otherwise eligible for an ongoing clinical study sponsored by Dren Bio and provided that other program eligibility criteria are also met.

Trial details
Type: Expanded AccessSponsor: Dren BioUpdated: Jun 15, 2026
Eligibility criteria

Not listed

Status: Recruiting

A Study of DR-0202 in Patients With Locally Advanced or Metastatic, Relapsed or Refractory Carcinomas

A phase 1a/1b, multicenter, open-label, dose escalation/expansion, multiple-dose study to evaluate the safety and activity of DR-0202 in patients with locally advanced or metastatic, relapsed or refractory carcinomas

Participants needed: 96
Trial details
Phase: Phase 1Age: 18+Biological sex: AllType: InterventionalSponsor: Dren BioUpdated: Jan 7, 2026Locations: 10
Eligibility criteria

Histologically confirmed epithelial cancer of the following tumor types: breast... [+8]

Major surgery within 28 days prior to Day 1 [+18]