Health Trials

Clinical trials

2

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

A Study of a Thyroid Hormone Receptor Beta Isoform (THRβ) Agonist and an Semicarbazide Sensitive Amine Oxidase (SSAO) Inhibitor, Alone and in Combination, in Adults With Presumed Metabolic Dysfunction-associated Steatohepatitis (MASH)

The primary objective of this trial is to evaluate the dose-dependent and comparative effects of ECC4703 (low and high dose), ECC0509 (low and high dose), and their combination on hepatic fat reduction as assessed by change in magnetic resonance imaging proton density fat fraction (MRI-PDFF) at Week 12.

Participants needed: 160
Trial details
Phase: Phase 2Age: 18-75Biological sex: AllType: InterventionalSponsor: EccogeneUpdated: Jun 5, 2026Locations: 58
Eligibility criteria

Adults between 18 and 75 years of age, inclusive, who can provide written inform... [+8]

Chronic liver disease other than metabolic dysfunction-associated steatotic live... [+9]

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Status: Recruiting

ECC4703 Food Effect and Relative Bioavailability Study in Healthy Adult Participants

This is a Phase I, open-label, randomized, single-dose, 2-part study designed to evaluate the food effect and relative bioavailability of ECC4703 in healthy adult participants.

Participants needed: 72
Trial details
Phase: Phase 1Age: 18-65Biological sex: AllType: InterventionalSponsor: EccogeneUpdated: Jan 16, 2026Locations: 1
Eligibility criteria

Healthy male and female participants [+8]

Females who are pregnant, planning to become pregnant, or breastfeeding during t... [+10]

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