Health Trials

Clinical trials

2

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

GPC3-Targeted T-Cell Therapy (ECT204) in Adults With Advanced HCC

This is an open-label, multi-center, Phase 1/2 clinical trial evaluating the safety, tolerability, and efficacy of ECT204, an investigational ARTEMIS® T-cell therapy, in adult subjects with GPC3-positive hepatocellular carcinoma (HCC) who have experienced disease progression on, or intolerance to, prior systemic therapy.

Participants needed: 60
Trial details
Phase: Phase 1, Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: Eureka Therapeutics Inc.Updated: Jun 9, 2026Locations: 8
Eligibility criteria

Histologically confirmed HCC, that is unresectable, recurrent, and/or metastatic... [+9]

Pre-existing illness (e.g., symptomatic congestive heart failure) that would lim... [+16]

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Status: Recruiting

ET140203 T Cells in Pediatric Subjects With Hepatoblastoma, HCN-NOS, or Hepatocellular Carcinoma

Open-label, dose escalation, multi-center, Phase I/II clinical trial to assess the safety/tolerability and determine the recommended Phase II Dose (RP2D) of ET140203 T-cells in pediatric subjects who are AFP-positive/HLA-A2-positive and have relapsed/refractory HB, HCN-NOS, or HCC.

Participants needed: 15
Trial details
Phase: Phase 1, Phase 2Age: 1-21Biological sex: AllType: InterventionalSponsor: Eureka Therapeutics Inc.Updated: Apr 9, 2025Locations: 2
Eligibility criteria

Histologically confirmed HB, HCN-NOS, or HCC with serum AFP >100ng/mL at the tim... [+8]

Recurrent HB who are candidates for complete surgical resection (e.g., isolated... [+11]

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