Clinical trials

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Condition / disease
Location
Status: Not yet recruiting

Tenecteplase (TNK) in the Treatment of Intracerebral Hemorrhage (ICH)

The overall purpose of this study is to look at the safety and effectiveness of administering Tenecteplase (TNK) into the brain bleed (hematoma) instead of another clot-dissolving drug known as recombinant tissue plasminogen activator (rtPA), which is the current standard practice. Clot dissolving (Fibrinolytic) drugs work to break down blood clots and have been found to improve health outcomes when applied directly into the hematoma within the brain. Patients who take part in this study will undergo the same surgical procedure that would normally be performed to treat them, but with the exception of TNK not rtPA.

Participants needed: 5
Trial details
Phase: Phase 1Age: 18-80Biological sex: AllType: InterventionalSponsor: Gaurav Gupta, MDUpdated: Apr 30, 2026
Eligibility criteria

Patient/legally authorized representative has signed the Informed Consent Form. [+9]

Presence of infratentorial parenchymal bleeding. [+23]