Health Trials

Clinical trials

2

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

A Long-Term Follow-up Study of the Severe Parkinson's Disease Patients Administered the IPS101A Gene Therapy Product.

The purpose of this study is to evaluate the long-term safety of IPS101A and to assess the durability of efficacy in subjects who received IPS101A.

Participants needed: 6
Trial details
Age: 50-80Biological sex: AllType: ObservationalSponsor: Innopeutics CorporationUpdated: Jul 1, 2026Locations: 1
Eligibility criteria

Subjects who were enrolled in the IPS101A-10 clinical trial and received IPS101A... [+1]

Subjects who decline to provide consent for participation in the long-term follo... [+1]

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Status: Recruiting

Phase 1 Clinical Trial to Evaluate the Safety, Efficacy, and Pharmacokinetics of IPS101A in Parkinson's Disease Patients

The purpose of this study is to evaluate the dose-related safety and tolerability of IPS101A, an adeno-associated virus (AAV) gene therapy, in patients with Parkinson's disease who exhibit severe functional impairment corresponding to Hoehn \& Yahr stages 4-5 and whose symptoms are not adequately controlled despite all available monotherapy and combination therapy options. In addition, the study aims to assess the maximum tolerated dose (MTD) of IPS101A, as well as its preliminary efficacy and pharmacokinetic (PK) characteristics.

Participants needed: 6
Trial details
Phase: Phase 1Age: 50-80Biological sex: AllType: InterventionalSponsor: Innopeutics CorporationUpdated: Apr 21, 2026Locations: 1
Eligibility criteria

Subjects who have a diagnosis of Parkinson's disease that meets the UK Parkinson... [+4]

Subjects with Parkinson's disease dementia (PDD) who meet the diagnostic criteri... [+5]

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