Clinical trials

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Condition / disease
Location
Status: Recruiting

Managing Chronic Tendon Pain by Metformin

The purpose of the current exploratory clinical trial is to determine the effect of oral ingestion of metformin (OIM) in non-diabetic patients with chronic Achilles tendon pain. The trial has two aims; 1) to assess the effects of OIM treatment on tendon pain, and 2) to determine the effects of OIM capsules on tendon healing and repair. Twenty participants will be treated with metformin capsules for 16 weeks combined with a home exercise program. A comparison group of 20 participants will be treated with placebo tablets along with home exercise program.

Participants needed: 40
Trial details
Phase: Phase 1Age: 18-50Biological sex: AllType: InterventionalSponsor: James WangUpdated: Jun 4, 2026Locations: 1
Eligibility criteria

Willing and able to provide informed consent for participation [+4]

Any intervention (corticosteroids or other orthobiologic intervention as injecti... [+19]