Health Trials

Clinical trials

2

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Phase 1/2 Study of OPK-88006 in Healthy and Presumed MASH Participants

Two-part Phase 1/2 study of OPK-88006, including an open-label SAD phase in healthy participants and a double-blind, randomized, placebo-controlled MAD phase in participants with presumed MASH, to evaluate safety, PK, and MASH related pharmacodynamic changes compared to placebo.

Participants needed: 30
Trial details
Phase: Phase 1, Phase 2Age: 18-75Biological sex: AllType: InterventionalSponsor: OPKO Health, Inc.Updated: Apr 6, 2026
Eligibility criteria

Adults aged 18-65 years. [+3]

Significant uncontrolled medical or psychiatric history. [+14]

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Status: Not yet recruiting

Pharmacokinetics, Pharmacodynamics, Safety and Tolerability Evaluation of CTAP101 Extended-release Capsules in Pediatric Participants

The goal of this clinical trial is to evaluate safety, tolerability, and how CTAP101 Capsules work to treat Pediatric Participants with Secondary Hyperparathyroidism, Stage 3 or 4 Chronic Kidney Disease and Vitamin D Insufficiency. The main questions it aims to answer are: 1. To assess the pharmacokinetics (PK) and Pharmacodynamics (PD) of CTAP101 Capsules 2. To investigate the safety and tolerability of CTAP101 Capsules Participants will take a daily dosage of CTAP101 Capsules at bedtime for 8 weeks.

Participants needed: 40
Trial details
Phase: Phase 2Age: 1-17Biological sex: AllType: InterventionalSponsor: OPKO Health, Inc.Updated: Mar 30, 2026Locations: 5
Eligibility criteria

Be 8 to <18 years of age with a body weight of ≥40 kg. [+16]

Kidney transplant within the 26 weeks preceding screening or kidney transplant r... [+8]

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