Clinical trials

5

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Clinical Efficacy Evaluation of Chaizhi Hewei Decoction in the Treatment of Non-Erosive Reflux Disease With Liver-Stomach Disharmony Syndrome

This study focuses on patients with NERD (gastroesophageal reflux disease) and liver-gallbladder disharmony syndrome as its research subjects. It conducts a randomized, double-blind, placebo-controlled clinical trial to evaluate the efficacy and safety of the Chai Zhi He Wei formula in terms of symptom improvement, quality of life, and adverse reactions. On one hand, this research aims to enhance the level of evidence-based medicine for TCM syndrome differentiation and treatment of NERD. On the other hand, it seeks to reduce the dosage of PPIs (proton pump inhibitors) or discontinue their use, addressing the side effects caused by PPI overuse, and serving as a leading example for TCM clinical research. Lastly, the study aims to optimize the efficacy of Tongjiang granules and address potential safety concerns, such as diarrhea.

Participants needed: 66
Trial details
Age: 18-70Biological sex: AllType: InterventionalSponsor: Xiyuan Hospital of China Academy of Chinese Medical SciencesUpdated: Apr 8, 2026Locations: 1
Eligibility criteria

Meet thediagnosis criteria for NERD; [+4]

Patients with active gastric or duodenal ulcers, gastritis with active bleeding,... [+7]

Status: Not yet recruiting

Clinical Study on the Intervention of Xuesaitong Soft Capsules in Post-Intervention Patients with Acute Coronary Syndrome and Clinical Research Protocol

To assess the effects of Xuesaitong soft capsules on platelet function, clinical efficacy, prognosis, and safety in the treatment of acute coronary syndrome, 400 patients with acute coronary syndrome who underwent PCI were treated with Xuesaitong soft capsules (mainly containing ginsenosides) for 12 weeks.

Participants needed: 400
Trial details
Phase: Phase 3Age: 18-80Biological sex: AllType: InterventionalSponsor: Xiyuan Hospital of China Academy of Chinese Medical SciencesUpdated: Feb 25, 2025Locations: 1
Eligibility criteria

Patients diagnosed with acute ST-segment elevation myocardial infarction, acute... [+3]

Uncontrolled hypertension after medication (systolic BP >180mmHg or diastolic BP... [+12]

Status: Recruiting

Study on the Effectiveness and Mechanism of Tong-Xie-Yao-Fang in Treating Diarrhea-predominant Irritable Bowel Syndrome

Traditional Chinese Medicine focuses on the main pathogenesis of liver depression and spleen deficiency, and treats them from the perspective of soothing the liver and strengthening the spleen to treat on Diarrhea-predominant irritable bowel syndrome (IBS-D) . The classic formula for treating is the Tong-Xie-Yao-Fang (TXYF). Based on metabolomics and metagenomics, the research group studied the intestinal flora and host co metabolism of TXYF in the treatment of diarrhea predominant IBS-D, in order to clarify the mechanism of TXYF in the treatment of IBS-D.

Participants needed: 60
Trial details
Phase: Phase 1Age: 18-70Biological sex: AllType: InterventionalSponsor: Xiyuan Hospital of China Academy of Chinese Medical SciencesUpdated: Dec 17, 2024Locations: 1
Eligibility criteria

IBS-D patients and healthy volunteers meeting diagnostic criteria; [+3]

Patients with serious heart, liver, kidney and other major organ diseases, hemat... [+7]

Status: Recruiting

Efficacy of Songling Xuemaikang Capsules on Grade 1 Hypertension: a Randomized Controlled Trial

The purpose of this study is: 1. To evaluate the efficacy of Songling Xuemaikang Capsules(SLXMKC) with grade 1 hypertension. 2. To reveal the potiential effects of SLXMKC on vascular function and structure of patients with grade 1 hypertension. 3. To explore the underlying mechanisms of the therapeutic effects of SLXMKC on the intervention of grade 1 hypertension.

Participants needed: 100
Trial details
Phase: Phase 4Age: 35-65Biological sex: AllType: InterventionalSponsor: Xiyuan Hospital of China Academy of Chinese Medical SciencesUpdated: Aug 20, 2024Locations: 5
Eligibility criteria

Age between 35-65 years old, male or female; [+3]

Significant liver and kidney dysfunction, ALT and AST upper the twice of normal... [+8]

Status: Recruiting

Study to Evaluate the Efficacy, Safety and Tolerability of Photodynamic Therapy(PDT) With Chlorin-e6 in Treating Moderate to Severe Acne

This study aims to evaluate the clinical efficacy, safety and tolerability of a photodynamic therapy(PDT) based on a new photosensitizer, Chlorin-e6, in the treatment of moderate to severe acne. The hypothesis is that the therapy has good efficacy, safety and tolerability.

Participants needed: 46
Trial details
Phase: Phase 2Age: 18-50Biological sex: AllType: InterventionalSponsor: Xiyuan Hospital of China Academy of Chinese Medical SciencesUpdated: Mar 15, 2024Locations: 1
Eligibility criteria

Subject is male or non-pregnant female 18 years of age and younger than 50 years... [+2]

People who are taking photosensitive drugs; [+9]