Effect of Ambient Temperature on Blood Glucose and Insulin Absorption in Adults With Type 1 Diabetes

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-45
SponsorInstitut de Recherches Cliniques de Montreal

About this trial

The goal of this clinical trial is to learn how different temperatures affect blood sugar levels in adults with type 1 diabetes. Climate change is causing more extreme hot and cold weather, and people with type 1 diabetes may be at higher risk during these temperature changes. The main questions it aims to answer are:

* Do different temperatures (cold, normal, or hot) change blood sugar levels in people with type 1 diabetes? * How does temperature affect insulin absorption in the body?

Researchers will compare three different temperature conditions to see how each affects blood sugar levels and insulin in the body.

Participants will:

* Complete a screening visit with body measurements and questionnaires * Attend 3 separate study visits, each in a different temperature setting: * Cold room (10°C/50°F) * Normal room temperature (23°C/73°F) * Hot and humid room (36°C/97°F with 65% humidity) * Sit for 2 hours in each temperature condition while researchers monitor their blood sugar, heart rate, and body temperature * Wear a continuous glucose monitor for 48-72 hours before each visit * Keep a diary of food, sleep, and activity for 24 hours before and after each visit

Each temperature visit is separated by at least 3 days. The study helps researchers understand if people with type 1 diabetes need special guidance for managing their blood sugar during extreme weather.

Eligibility criteria

Qualifiers

Diagnosis of type 1 diabetes for more than 2 years

Ability to provide verbal and written informed consent

Ability to speak and understand French

Disqualifiers

Recent and/or unstable health condition (less than 3 months) prior to enrolment

Any viral infection at time of participation

Chronic illness other than type 1 diabetes (for example: pulmonary disease, cardiovascular disease, cancer)

Health condition not controlled by medication

Trial design

Treatments tested in this trial

  • Environmental Temperature Exposure

Treatment groups

30 Participants
are divided into 3 treatment groups

Sponsors and collaborators

Institut de Recherches Cliniques de Montreal

Lead sponsor

Cardiometabolic Health, Diabetes and Obesity Research Network

Collaborator

Centre EPIC

Collaborator