Clinical trials

2

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Safety and Efficacy of Injectable Klotho Plasmid Gene Therapy in Humans

The purpose of this study is to investigate the safety and efficacy of a gene therapy for Klotho, delivered via a nonviral plasmid in healthy adult volunteers. Additionally, this study seeks to understand the cognitive and health benefits of the Klotho gene therapy.

Participants needed: 24
Trial details
Phase: Phase 1Age: 23-90Biological sex: AllType: InterventionalSponsor: MinicircleUpdated: Feb 17, 2026Locations: 2
Eligibility criteria

Participant is open to morphological change [+3]

Women of childbearing potential who are unwilling or unable to use effective con... [+4]

Status: Recruiting

Safety and Efficacy of Klotho and Follistatin Gene Therapy

The purpose of this study is to investigate the safety and efficacy of a combination klotho and follistatin gene therapy, delivered via a nonviral plasmid in healthy adult volunteers. Additionally, this study seeks to understand the cognitive and health benefits of this gene therapy.

Participants needed: 30
Trial details
Phase: Early Phase 1Age: 50-80Biological sex: AllType: InterventionalSponsor: MinicircleUpdated: Jan 8, 2026Locations: 2
Eligibility criteria

Adults aged 50 to 80 years [+6]

Currently enrolled in another clinical trial [+8]